STUDENTS

CURRENT STUDENTS:

PAST STUDENTS:

2025

Doctoral
Kheireddin Mufti	Pharmacogenomic study of vincristine-induced peripheral neuropathy in patients with pediatric cancers
Kevin Jeffers	Characterization of the yeast Vps13 VAB domain in regard to its regulation of PxP adaptor recruitment and Vps13 function
Master’s
Hannah Illing	Placental DNA methylation patterns associated with pathology and maternal age
Jiaqi Wu	Assessing the safety and efficacy of PODO83 and PODO447-ADC as cancer therapeutics
Hailey Findlay Black	Characterization of a synonymous DNA variant in the HTT gene and its effect on onset of Huntington disease
Kennedy Austin	Empowerment in Adolescent Patients with a Disability/Chronic Condition: A Scoping Review

2024

Doctoral
Porter, Vanessa	Discovery of HPV-associated genomic alterations in cervical cancer

2023

Doctoral
Scott, Erika	Elucidating genetic predictors for anthracycline-induced cardiotoxicity and cisplatin-induced ototoxicity in pediatric and adult cancer patients to improve patient treatment decisions
Carlaw, Tiffany	Therapeutic genome editing for the treatment of genetic diseases: Testing the safety and effectiveness of CRISPR/cas9 therapeutic base editing
Cyrus, Sharri	Polycomb Repressive Complex 2 Related Syndromes: Functional Studies of Human Gene Variants in Drosophila
Shortill, Shawn	Identification and Functional Analysis of the Endosomal vine complex in Saccharomyces cerevisiae
Schaffner, Samantha	Associations of DNA Methylation with Individual Differences in Parkinson’s Disease Susceptibility
Dziurdzik, Samantha	Membrane contact site targeting and functions of Vps13 and related bridging lipid transporters
Thomson, Sarah	Novel approaches for therapeutic modulation of gene expression in Huntington’s disease
Gibson, Kristen	Assessment of biological markers to aid subtype classification in pediatric primary systemic vasculitis
Mirjalili, Zeinab	Successful Gene Editing in a Novel Mouse Model of Aniridia Towards Prevention of Blindness
Kumar, Arun	DNA damage induced SUMOylation regulates intranuclear protein quality control in Saccharomyces cerevisiae
Akbari, Vahid	Detecting DNA methylation using nanopore sequencing : from genome-wide analysis to haplotype-resolved and parent-of-origin phasing
Master’s
Jenkins, Kyle	Simulating chromoanagenesis for tool development and testing
Cheung, Chun Wai	Characterization of DPP4⁺ fibroadipogenic progenitors in skeletal muscle
Lin, Dorothy	Dispersed measures of cord blood DNA methylation do not reflect third trimester bisphenol exposure
Sabatino, Brendil	Characterization of the transcriptomic response to acute starvation in the C. elegans hypodermis
Adair, Bethany	Development of a CRISPR gene correction strategy for aniridia employing a minimally humanized mouse embryonic stem cell-based disease model

2022

Doctoral
Doering, Kelsie	The Caenorhabditis elegans nuclear hormone receptor NHR-49 functions in stress response pathway regulation
Eskandari-Nasab, Ebrahim	Prosurvival role of CASPASE3 in normal and malignant human mammary cells
Wang, Fangwu	Characterization of the lympho-neutrophil/monocyte restriction process in human cells
Ha, Amanda	Functional characterization of Mest and its imprinted gametic differentially methylated region.
Hasbullah, Jafar	An investigation of the role of pharmacogenetics in the development and prevention of anthracycline-induced cardiotoxicity
Master’s
Dawo, Sebastian	Salmonella Typhimurium Based Genome-Wide CRISPR/CAS 9 Knockout Screen to Study p16 Degradation
Elazabbi, Nairuz	Allele-specific expression differences in the mouse embryonic hindbrain following prenatal alcohol exposure
Theberge, Emilie	Investigating sex differences in the polygenic risk of major depressive disorder and shared associations with cardiovascular disease
Horbach Marodin, Rafaela	Genetic interactions between cohesin and DNA damage response pathways in Saccharomyces cerevisiae

2021

Doctoral
Amitzi, Leanne	DDX11 Helicase as a Synthetic Lethal Cancer Therapy Target
Pillsworth, Jessica	Adult-Type Granulosa Cell Tumours of the Ovary: A Foxl2-Centric Disease
Master’s
Newman-Simmons, Avery	Investigating the Genetic Contributions to Familial Intracranial Aneurysms in a First Nation from Northwestern British Columbia
Riyadh, Omer	Uncovering factors implicated in oncogenic NRAS modification  by analyzing large scale functional genomic data sets
Grant, Peter	Investigating Trends in Out-of-Pocket Pay for Out-of-Province Genetic Testing in British Columbia

2020

Doctoral
Refaeli, Ido	Generation, characterization and optimization of mouse models for genetic glomerular disease
Dixon-McDougall, Thomas	Functionality of domains of XIST and their role in establishing chromosome inactivation
Brown, Joshua	Diverse functions of Rtt107 in the Saccharomyces cerevisiae DNA damage response
Canals Hernaez, Diana	Investigation of the Role of Podocalyxin in Cancer Progression and Its Potential as a Cancer Therapeutic
Del Gobbo, Giulia	Genomic Profiling in the Placenta: Toward a Greater Understanding of Genetic Variation Contributing to Placental Insufficiency and Fetal Growth Restriction
Master’s
Dever, Kristy	A broader role for the RNAPII phosphatase, FCP1, in transcription regulation
Lin, Jennifer	The pharmacogenomics of hepatitis C: optimizing efficacy and safety on treatment
Farag, Roula	Molecular mechanisms of BAP1 mutations in uveal melanoma

2019

Doctoral
Collins, Sorcha	The role of the carnitine palmitoyltransferase 1A (CPT1A) p.P479L variant in Inuit infant and child health outcomes in Nunavut
Kadhim, Alexandre	Investigating the role of transcriptional coactivator MED15 in beta cell maturation
Al Shekaili, Hilal Hamed	Investigating vitamin B6-dependent epileptic encephalopathies in human patients and a mouse model
Dixon, Katherine	Molecular characterization and genetic diagnosis of cancer predisposition syndromes using genome and transcriptome sequencing
Richard Albert, Julien	Application of an allele-specific pipeline to study DNA methylation inheritance and dynamics in the early embryo
Jones, Samantha	Characterization of environmental and genetic factors in multiple-case lymphoid cancer families
Tam, Annie S.	The conserved role of RNA splicing factors in genome maintenance
Urtatiz Gongora, Oscar	Oncogenic GNAQ and BRAF in epidermal versus non-epidermal melanocytes
Goodman, Sarah	Contributions of intrinsic and environmental factors to early life DNA methylation
Master’s
Jain, Fagun	Two novel genetically engineered mouse models for uveal melanoma with liver metastasis
Kwan, Harwood	An investigation into the non-coding genomic landscape and effects of chemotherapeutics in pre-treated advanced cancers
Jensen, Kristoffer	HP1-mediated transcriptional silencing of ERVs and genes in mouse embryonic stem cells
Soundara Rajan, Jeffy	Investigating mouse motor activity and learning behavior using quantitative trait locus (QTL) analysis to elucidate the genetic underpinnings of developmental coordination disorder (DCD)
Gupta, Ishita	Spatiotemporal characterisation of some transcriptional signatures in early cerebellar development
Vermeulen, Michael	Improving and estimating Y chromosome loss in blood and brain tissues using high-throughput sequencing

2018

Doctoral
Barbaian, Artem	Endogenous retroviruses drive transcriptional innovation in human cancer
Peeters, Samantha	Modelling human escape from X-chromosome inactivation in mouse
Konwar, Chaini	Molecular profiling of acute chorioamnionitis-affected placentas: insights into genomic variation underlying a common preterm birth condition
Singh, Chaahat S. B.	Mechanism underlying dysregulated cerebral vessel growth in Alzheimer’s disease
Hickmott, Jack	rAAV9 mediated PAX6 gene transfer temporarily reverses corneal epithelial thinning in a mouse model of aniridia
Islam, Sumaiya	Tissue-specific investigations on DNA methylation variation in human neurobiological diseases
McEwen, Lisa	DNA methylation variation across the human life course
Wong, Chi Kin	The role of p300 transcriptional coactivators in pancreatic beta cells
Master’s
Porter, Vanessa	Targeting Autophagy in Chronic Myeloid Leukemia Through Inhibition of the Core Autophagy Protein ATG4B
Shomer, Naomi	A Regulatory Mechanism of Zinc Homeostasis Involving the Mediator Subunit MDT-15 and the Transcription Factor HIZR-1

2017

Doctoral
Chen, Carol	Interphase Histone H3 Serine 10 Phosphorylation in Mouse Embryonic Stem Cells
Cohen, Ana	Detailed Phenotyping and Next-Generation Sequencing for Characterization of Rare Overgrowth Syndromes
Fam, Andrew	Tyrosol-DNA Phosphodiesterase1 (TDP1): From Spinocerebellar Ataxia to Roles in Mitochondrial DNA Repair and Cancer Therapy
Kay, Christopher	Population Genetics and Allele-Specific Silencing of the Huntington Disease Mutation
Lussier, Alexandre Andre	Epigenetic Signatures of Prenatal Alcohol Exposure
Wilson, Samantha	Genetic and Epigenetic Profiling of Placental Insufficiency: Identifying Biomarkers of Preeclampsia and Intrauterine Growth Restriction
Zhang, Peter	Transcriptional Regulation in the Development of the Cerebellum and Cerebellar Granule Cells
Zhang, Regan-Heng	The Lysine Methyltransferase EHMT2/G9a in Mesenchymal Development
Master’s
Ellis, Samantha	Introduction of the Antigen Presentation Machinery Using Novel Small Molecules
Hitchcock, Emma	Next Generation Sequencing to Determine a Genetic Cause of Familial Intracranial Aneurysms
Little, Natasha	Characterization of IAPLTR1 Subclasses and Bidirectional Promoter Activity: “Making Sense of it All”
Reytan, Sivan	Identification of Cancer Relevant Synthetic Genetic Interactions with Cohesin Mutations in Saccharomyces Cerevisiae
Segovia Ugarte, Romulo	Synthetic Hypermutation: Gene-Drug Mutation Rate Synergy Reveals a Translesion
Selmer, Laura	Intracranial Manifestations in Neurofibromatosis 1
Szetzo, Rochelle	Telomere Position Effect in Embryonic Stem Cells: Heterogeneity, Imprinting, and Modifier Screen
Turner, Kelly	Assessment of a Potential Therapeutic Target in the Hedgehog Pathway for the Eradication of Primitive Chronic Myeloid Leukemia Cells
Yuen, Michael	Mapping Complex Genomic Translocations Using Strand-seq

2016

Doctoral
Chung, George Chih Hsuen	Genetic Determinants of Genome Stability and Crossover Distribution in the Nematode Caenorhabditis elegans
Connolly, Colum	Microglial Dysfunction Induced by Mutant Huntingtin
Dastan, Jila	Exome Sequencing for Understanding Phenotypic Variability in Subjects with 16p11.2 CNV
Grants, Jennifer	Roles of the Mediator Subunit CDK-8 in Developmental and Physiological Responses in Caenorhabditis elegans
Kaurah, Pardeep	Hereditary Diffuse Gastric: Cancer Risk and the Personal Cost of Preventative Surgery
Ladha, Safia	Impact of Caspase-6 Modulation on Huntington Disease Phenotypes in the YAC128 Mouse Model
Trinh, Joanne	Identification of Genetic Modifiers in Lrrks2 Parkinsonism
Yeung, Joanna	The Role of Pax6 and Wls in Rhombic Lip Compartmentation and Cerebellar Development
Master’s
de Goede, Olivia	Identifying Epigenetic Associations with Cell Type and Gestational Age in the Neonatal Immune System
Lee, Ka Young	Functional Characterization of Gene Regulation by NHR-49
Pilsworth, Jessica	Gene Expression and Mutation Profiles Define Novel Subclasses of Cytogenetically Normal Acute Myeloid Leukemia

2015

Doctoral
DeSouza, Rebecca	Characterization of the Huntingtin Gene Promoter and Huntingtin Transcriptional Regulation
Heppner, Jonathan	Early Disruption of the Extracellular Matrix in Murine Mucopolysaccharidosis I
Lin, David Tse-Shen	Characterization of Novel Regulatory Components in the Dynamic Protein Palmitolytion Cycle
Liu, Sheng	Transcriptional Repression of Retrotransposons in Mouse Germline
Rothe, Katharina	Characterization of Novel Therapeutic Targets in Chronic Meyloid Leukemia
Tharmarajah, Grace	The Role of Adamts9 in Melanoblast Migration and Modification of the Skin Proteome
Thompson, Peter	Transcriptional Silencing of Endogenous Retroviruses by the Novel Lysine Methytransferase Co-repressor hnRNP K
Master’s
Ang, Sidney	Identification and Characterization of Dosage Mutator Genes in Saccharomyces cerevisiae
Huff, Ryan	Generation and Characterization of a Lysine (K)-specific Methyltransferase 2D Knockout Human Cell Line

2014

Doctoral
Esmailzadeh, Sharmin	The role of BIN1 in the Regulation of Cell Proliferation, Apoptosis and Tumor Formation in Cutaneous T-Cell Lymphoma
Jett, Kimberly	Vascular Function in Neurofibromatosis 1
Lee, Joshua	Multiple Sclerosis in Asian Populations : The Genetic and Environmental Determinants of Variable Susceptibility and Clinical Profile
Miller, Michelle	Validation of Two Novel Mouse Models of Conditional Meis1 Deletion to Study Roles in Adult Mouse Hematopoiesis
Poon, Anna Fong-Yee	Genetic Architecture of Neurogenesis in the Adult Mouse Forebrain: Insights from Quantitative Trait Locus Analyses
Master’s
Billings, Raewyn	Stimulating Human Tumour Heterogeneity using Cancer Cell Line Mixtures
Greenwood, Talitha	Gene Discovery in Individuals from Families Indicative of Mendelian Forms of Late-Onset Alzheimer Disease
Huang, Jenny Li-Ying	Ocular Melanocytes respond to Oncogenic GNAQQ209L differently compared to Epidermal and Dermal Melanocytes in Mice
Kaur, Achint	The Role of Sterol 12α- hydroxylase (Cyp8b1) in Glucose Homeostasis
Lee, Jong Wook	A Genome-Wide Association Study of Cisplatin-Induced Hearing Loss in Children
Moshgabadi, Noushin	Identification of Synthetic Cytotoxic Interactions to Improve the Efficacy of DNA Damaging Therapeutic Agents
Tam, Annie	Whole Genome Mutational Profiling of the Chemotherapeutic Agent Mitomycin C
Ye, Xin	Mapping a New Locus for Non-Syndromic Strabismus with High-Throughput Genome Analysis

2013

Doctoral
Baradaran-Heravi, Alireza	Schimke Immuno-osseous Dysplasia: Association of SMARCAL1 Mutations with Genetics and Environmental Disturbances of Gene Expression
de Leeuw, Charles	Development of Tools in Mouse for Future Gene Therapy: Promoters for the CNS, and Novel Expression Models of Neural Stem Cell Regulator, NR2E1
Hanna, Courtney	Patterns of DNA Methylation on the Human X Chromosome and Use in Analyzing X-Chromosome Inactivation
MacIsaac, Julia	Developmental Consequences of Imprinted Transcription at the Mest Locus
Mazarei, Gelareh	Investigating the role of Indoleamine 2,3 dioxygenase in Huntington disease
Master’s
Blair, John	DNA methylation studies of preeclamsia and related conditions
Chapman, Andrew	Transcriptional regulation of the XIST locus
Jacob, Karen	The function of the imprinted transcription factor ASCL2 in mouse trophoblast development
Kelsey, Angela	Mechanisms for XIST RNA cis-localisation
Stepien, Katarzyna	Prenatal Alcohol Exposure Programs Steady-State Gene Expression and the Gene Expression Response to Inflammation in the Adult Rat Brain
Yoo, Janice	The effects of cerebellar hemorrhage on the development of the postnatal cerebellum

2012

Doctoral
Cotton, Allison	Patterns of DNA Methylation on the Human X Chromosome and Use in Analyzing X-Chromosome Inactivation
Earp, Madalene	Genetic Studies to Discover Common Variants Associated with Epithelial Ovarian Cancer Risk and Variation in Age of Natural Menopause
Kang, Martin	Post-transcriptional Regulation of ABCA1
Minks, Jakub	Role of XIST RNA and Its Interacting Protein Partners in Gene Silencing
Semaka, Alicia	Genetic Counselling Implications for Intermediate Allele Predictive Test Results for Huntington Disease
Master’s
Chowdhury, Miraj	Tyrosyl-DNA Phosphodiesterase 1 (TDP1): A Rhabdomyosarcoma Therapeutic Target and Mitochondrial DNA Repair Enzyme
Chun, Stella	Identification and validation of CDK13 interacting proteins
Fisher, Emily	The Epidemiology of Huntington Disease in British Columbia
Fornika, Dan	Mitochondrial Genome Variation and Healthy Aging
Lepage, Sarah	Analysis of the Mechanism of Maintenance of the H3K27 Trimethylation Mark Using a Novel Chromatin Targeting System
Yang, Christine	DNA methylation demonstrates spread of X-chromosome inactivation to human transgenes

2011

Doctoral
Burston, Helen	Genome-wide Analysis of Endocytic Recycling inS. cerevisiae
Deo, Mugdha	Role of Nf1 Signaling in Regulating Pigmentation in Mice
Lee, Connie	The role of imprinted genes in mouse models of IUGR
Leung, Danny	Transcriptional Silencing of Endogenous Retroviruses: Interplay Between Histone H3K9 Methylation and DNA Methylation
McLellan, Jessica	A Cross Species Approach to Identify Potential Therapeutic Targets through Synthetic Lethal Interactions
Oh-McGinnis, Rosemary	Regulation of Genomic Imprinting in the Mouse Placenta
Yuen, Ryan	Epigenetics of Human Fetal and Placental Development
Zahir, Farah	The Pathogenicity of Copy Number Variants in Children with Intellectual Disability
Master’s
Brind’Amour, Julie	Analysis of the Mechanism of Maintenance of the H3K27 Trimethylation Mark Using a Novel Chromatin Targeting System
Decker, Michelle	Telomere Length and Dynamics in Hutchinson-Gilford Progeria Syndrome
Miceli, Katharine	Who’s the Boss? An Investigation into the Complex Relationship between Endogenous Retroviruses and Nearby Genes
Sekulovic, Sanja	Analysis of the Mechanism of Maintenance of the H3K27 Trimethylation Mark Using a Novel Chromatin Targeting System

2010

Doctoral
Alwan, Sura	Risk Assessment of Birth Defects in Human Pregnancy
Degeer, Donna	Characterization of a Novel Fluorescent Reporter of Genomic Imprinting in the Mouse
Gallo, Marco	Misc/OCG is a New Stress Response Gene and Regulator of Apoptosis, Germline Stem Cell Proliferation and Insulin Secretion
Jensen, Victor	Novel Components of the Dauer Larva Developmental Signaling Pathway in Caenorhabditis elegans
Schuetz, Johanna	Genetic Variation in Lymphocyte Life and Death Genes and Risk of non-Hodgkin Lymphomas
Jones, Meaghan	XIST/Xist Induced Epigenetic Events in Somatic Cells
Long, Michael	Development of Strategies to Enhance the Contribution of Hematopoietic Cells to Skeletal Muscle Repair.
Morrissy, Anca	Bioinformatic Analysis of Cis-Encoded Antisense Transcription
Pouladi, Mahmoud	On the Modulation of Excitotoxicity as a Therapeutic Approach for the Treatment of Huntington Disease
Thorogood, Nancy	XIST/Xist Induced Epigenetic Events in Somatic Cells
Vrljicak, Pavel	Genomic Analysis of Embryonic Heart Development in the Mouse
Young, Fiona	The Biology and Expression of Huntingtin-Interacting Protein 14
Master’s
Bourque, Danielle	Imprinted Genes in the Placenta and Obstetrical Complications
Degeer, Donna	Characterization of a Novel Fluorescent Reporter of Genomic Imprinting in the Mouse
Hirukawa, Alison	The role of SHIP1 in modulating disease severity in the K/BxN serum transfer model of rheumatoid arthritis
Huang, Jim	The characterization of atm-1 in Caenorhabditis elegans
Lohn, Zoe	A New Role for the Tumour Suppressor, lin-35, During Meiotic Recombination in Caenorhabditis elegans
Ngai, Tiffany	The Low-density Lipoprotein Receptor Knock-out Mouse: A Model for the Study of Energy Balance
Plamondon, Jenna	Genetic and Epigenetic Factors in a Mouse Model for Multifactorial Cleft Lip
Thiele, Jenny	Generation and characterization of embryonic stem cell lines derived from the YAC128 mouse model of Huntington disease

2009

Doctoral
Chang, Samuel	Identification and characterization of cis-acting regulatory elements for human XIST
Griffith, Malachi	Methods for Transcript Variant Discovery and Alternative Expression Analysis – Application to the Study of Fluorouracil Resistance in Colorectal Cancer
Haddon, Jamie	Mast cells : homeostatic regulation, activation, gene expression, surface antigens, and role in allergic disease
Lam, Karen	The role of palmitoylation in endoplasmic reticulum transport and quality control of the yeast polytopic protein Chs3
Pugh, Trevor	Analysis of primary human cancers: from single genes to whole transcriptomes
Wong, Bibiana	Evaluating the Effects of Variable NR2E1 Levels on Gene Expression, Behaviour, and Neural and Ocular Development
Master’s
Borrie, Adrienne	A mutational screen of NR2E1 in patients with Aniridia, Peters’ Anomaly, and related eye disorders.
Riendeau, Noemie	Autism Spectrum Disorders: Identification of Novel Microdeletions and Microduplications and their Associated Phenotypes
Tkac, Jan	Detection of Telomeric DNA Circles in Human ALT Cells Using Rolling Circle Amplification
Toub, Omid	Initial characterization and Intracellular localization of two suppressors of position effect variegation in Drosophila melanogaster, S2214 and puckered

2008

Doctoral
Bretherick, Karla	Genetic factors in premature ovarian failure
Griffith, Obi	Identification of gene expression changes in human cancer using bioinformatic approaches
Rouhi, Arefeh	A role for epigenetic modifications in the maintenance of mouse Ly49 receptor expression
Ryan, Jane	A Genome-Wide Linkage Scan and Targeted Family-Based Association Analysis of Dyslexia
Master’s
Elves, Rachel	Consequences of mitotic loss of heterozygosiy on genomic imprinting in mouse embryonic stem cells
Kennah, Erin	Identification of differentially expressed genes in AHL-1-mediated leukemic transformation in human cutaneous T-cell lymphoma
Koochek, Maryam	Sub-microscopic chromosomal imbalances in idiopathic autism spectrum disorder (ASD)
Mazarei, Gelareh	Identification of Novel Striatal-Enriched Transcripts and their Analysis in Huntington Disease
Miller, Shelley	Development of embryonic stem cells expressing endogenous levels of a fluorescent protein fused to the telomere binding protein TRF1
Wagner, Laura	Silencing mutant huntington by RNA interference for the treatment of Huntington disease

2007

Doctoral
Bakovic, Silvia	Ex vivo expansion of hematopoietic stem cells for use in nonmyeloablative transplantation
Brunham, Liam	The impact of genetic variation in ABCA1 on cholesterol metabolism, atherosclerosis and diabetes
Tarailo, Maja	Spindle assembly checkpoint and chromosome stability in Caenorhabditis elegans
Youds, Jillian	Roles of the DOG-1 and JRH-1 helicase-like proteins in DNA repair in Caenorhabditis elegans
Master’s
Harbord, Sara	X Chromosome Abnormalities in Breast and Ovarian Cancer

2006

Doctoral
Graham, Rona	In vivo characterization of caspase resistant huntingtin: Insights into the pathogenic mechanism of Huntington disease
Kumar, Ravinesh	Ex vivo expansion of hematopoietic stem cells for use in nonmyeloablative transplantation
Mar, Lynn	Role of TGIF in cell cycle control and establishment of laterality
Nielsen, Julie	The role of podocalyxin in adhesion and cell morphogenesis
Tucker, Tracy	Pathogenesis of neurofibromatosis 1 associated neurofibromas
Yuen, Karen	Identification and characterization of chromosome instability mutants in the yeast Saccharomyces cerevisiae and implications to human cancer
Master’s
Randall, Derrick	Identification of a Serum Biomarker for Mucopolysaccharidosis
Sipahimalani, Payal	Variation in ATM and genetic susceptibility to non-Hodgkin lymphoma
Quint, Desiree	Aberrant Hypermethylation of Xq12 in Lymphoma
Wu, Joyce	YB-1 is a Downstream Component of the PI3K/Akt Signaling Pathway and Regulates EGFR in Breast Carcinoma: A Mechanism for Breast Cancer Growth

2005

Doctoral
Cheng, Benjamin	Identificaton of novel factors required for chromosome segregation in budding yeast
Cheung, Iris	Instability of G-rich DNA in Caenorhabditis elegans
Gair, Jane	Genetic mechanismss of nondisjunction in humans
Gurevich, Rhonna	Functional analysis of the NUP98- Topoisoerase 1 (NUP98-TOP1) fusion gene in the pathogenesis of leukemia
Murray, Angus	Functional genomics of the A600 locus in Leishmania mexicana
Pleasance, Erin	Identification and analysis of programmed cell death genes in Drosophila melanogaster and human cancer using bioinformatic analysis of gene expression data
Van Raamsdonk, J.	Characterization and treatment of mouse models in Huntington disease
Master’s
Schnerch, Angelique	Analysis of Undifferentiated Human Embryonic Stem Cell Lines Using Serial Analysis of Gene Expression
Hoscheit, Julia	Multifactorial genetics of exencephaly in the SELH/Bc mouse strain
Yen, Ziny	Comparative sudies of X inactivation within Eutheria

2004

Doctoral
Dickstein, Dara	The Role of Inflammation and amyloid beta in Alzeimer Disease Pathology

2003

Doctoral
Chopra, Vikramjit	The HIP1 family of cytoskeletal-associated proteins
Chow, Jennifer	XIST and its role in X-chromosome inactivation
Chu, Pak-Yan (Pat)	Effect of c-kit and flt-3 overexpression on primitive hematopoietic cells
Penaherrera, Maria	X-chromosome inactivation pattern in human extraembryonic and fetal tissues
Russell, Chris	Transgenic expression of human alpha-L-iduronidase in mouse and characterization of the long term pathophysiology of murine alpha
Wilhelm, Brian	The genomic organization and transcriptional regulation of natural killer receptor genes
Master’s
Lee, Tsz Kin	Bioinformatic analysis on NF1 transcriptional regulation

2002

Doctoral
Anderson, Cathy	Variable X inactivation of the human TIMP1 gene
Faulkes, Sharlene	Site-directed integration using the Cre/lox system in hematopoietic and embryonic stem cells
Master’s
Kwok, Ed	XIST and macroH2A1.2 in hybrid cells

2001

Doctoral
Szudek, Jacek	Analysis of variable expressivity in Neurofibromatosis
Parker, Jodey	The Caenorhabditis elegans homologue of huntingtin interacting protein 1 has multiple roles in development

2000

Doctoral
Moslehi, Roxana	Genetic studies of ovarian cancer in Jewish women

1999

Doctoral
Hodgson, John	Production and characterization of YAC transgenic mice expressing the normal and mutant Huntington’s disease gene
Bruskiewich, R.	Genetic mapping, functional analysis and bioinformatics of Werner syndrome locus (WRN)

1998

Doctoral
Gagne, Eric	Identification and the relationship between mutations in the lipoprotein lipase gene, dyslipidemia and coronary heart disease
Nelson, Tanya	Molecular and genetic analysis of human 8p inversion duplication chromosomes
Kowalski, Paul	Novel genetic effects of a human endogenous retrovirus inserion

1997

Doctoral
Ginzinger, David	Lipoprotein lipase deficiency in a colony of domestic cats

1996

Doctoral
Pawliuk, Robert	Growth properties and genetic manipulation of murine hemopoietic stem cells

1995

Doctoral
Biaoyang, Lin	Cloning and characterization of genes in the proximal candidate region for the Huntington disease in mouse and human